CHLORAMBUCIL is a chemotherapy drug. It slows the growth of cancer cells. This medicine is used to treat cancer like some leukemias and lymphomas.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
blood disorders
head injury
infection (especially a virus infection such as chickenpox, cold sores, or herpes)
recent or ongoing radiation therapy
seizures
an unusual or allergic reaction to chlorambucil, other chemotherapy, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
This medicine may also interact with the following medications:
nalidixic acid
medicines to increase blood counts like filgrastim, pegfilgrastim, sargramostim
vaccines
Talk to your doctor or health care professional before taking any of these medicines:
acetaminophen
aspirin
ibuprofen
ketoprofen
naproxen
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
In some cases, you may be given additional medicines to help with side effects. Follow all directions for their use.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.
Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
Men should inform their doctor if they wish to father a child. This medicine may lower sperm counts.
What side effects may I notice from this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding.
signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine
signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine
signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness
agitation
breathing problems
confusion
cough that does not go away
dark urine
hallucinations
mouth sores
redness, blistering, peeling or loosening of the skin, including inside the mouth
seizures
tingling, pain or numbness in the hands or feet
tremors
trouble passing urine or change in the amount of urine
trouble with balance, walking
vomiting
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea
loss of appetite
missed menstrual periods
nausea
This list may not describe all possible side effects.
Where should I keep my medicine?
Keep out of the reach of children.
Store in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.
