• ENDOBLOC T is used to treat pulmonary arterial hypertension (PAH) in adults
• PAH is high blood pressure in the blood vessels (the pulmonary arteries) that carry blood from the heart to the lungs
Talk to your doctor before taking this medicine, if you:
• are allergic to Ambrisentan, Tadalafil, soya, or any of the other ingredients of this medicine
• have scarring of the lungs, of unknown cause (idiopathic pulmonary fibrosis)
• have anaemia (a reduced number of red blood cells)
• have swelling in the hands, ankles or feet caused by fluid (peripheral oedema)
• suffer from lung disease where the veins in the lungs are blocked (pulmonary veno-occlusive disease)
• have heart problems such as angina (chest pain), heart failure, irregular heartbeats or have had a heart attack
• have low blood pressure or high blood pressure that is not controlled
• have had a stroke
• have kidney or liver problems
• have stomach ulcers
• have vision problem, including any damage to your optic nerve
• have ever had hearing problems such as ringing in the ears, dizziness or loss of hearing
• have a deformed penis shape or Peyronie’s disease
• have had an erection that lasted more than 4 hours
• have blood cell problems such as sickle cell anemia, multiple myeloma or leukemia
• Do not take ENDOBLOC T if you are pregnant or planning to become pregnant
• Do not breast-feed while you are taking this medicine
ENDOBLOC T is not recommended for children and adolescents aged under 18 years as the safety and effectiveness is not established in this age group
• ENDOBLOC T may cause side effects, such as low blood pressure, dizziness, tiredness, that may affect your ability to drive or use machines
• Do not drive or use machines if you are feeling unwell
Tell your doctor if you are taking, have recently taken or might take any other medicines such as:
• cyclosporine (a medicine used after transplant or to treat psoriasis)
• rifampicin (an antibiotic used to treat tuberculosis)
• other medicines used to treat pulmonary hypertension such as iloprost, epoprostenol, sildenafil
• nitrates or guanylate cyclase stimulators
• medicines used to treat hypertension
• protease inhibitors, used to treat HIV infection, such as ritonavir
• ketoconazole, itraconazole (medicines used to treat fungal infection)
• phenobarbital, phenytoin, carbamazepine used to treat fits
• other medicines for erectile dysfunction (impotence)
• Always take this medicine exactly as your doctor has told you to
• Swallow the medicine with a glass of water
• Do not split, crush or chew the medicine
If you take more ENDOBLOC T
• If you take more ENDOBLOC T, you may be more likely to have side effects, such as headache, flushing, dizziness, nausea (feeling sick), or low blood pressure that could cause light-headedness
• Contact your doctor or go to nearest hospital immediately
If you forget to take ENDOBLOC T
• If you forget a dose of ENDOBLOC T, just take the medicine as soon as you remember, then carry on as before
• Do not take two doses at the same time to make up for a forgotten dose
If you stop taking ENDOBLOC T
• Do not stop taking ENDOBLOC T without your doctor's advice
Like all medicines, this medicine can cause side effects, although not everybody gets them.
• allergic reactions marked by rash or itching and swelling (usually of the face, lips, tongue or throat) which may cause difficulty in breathing or swallowing
• swelling (oedema), especially of the ankles and feet
• heart failure (this is due to the heart not pumping out enough blood, causing shortness of breath, extreme tiredness and swelling in the ankles and legs)
• decreased eyesight in one or both eyes
• sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness
• erection that lasts more than 4 hours (with or without pain)
Like all medicines, this medicine can cause side effects, although not everybody gets them.
• anaemia (reduced number of red blood cells) marked by tiredness, weakness, shortness of breath and generally feeling unwell
• hypotension (low blood pressure)
• flushing (redness of the skin)
• vomiting
• rash
• chest pain/discomfort
• blurry or other changes to vision
• fainting
• running nose
• constipation
• ringing in the ears (tinnitus)
Like all medicines, this medicine can cause side effects, although not everybody gets them.
• liver injury
• sudden hearing loss
• Store at room temperature (15-25ºC)
• Keep this medicine out of the reach of children
• Do not use this medicine after the expiry date
人々は、体の内部時計を調節するために、メラトニンを使います。予定が毎日の仕事を変える人々で睡眠覚醒循環を調節するために、それが時差ぼけのために使われます。それが、盲人が1昼夜サイクルを確立するのを援助するために使われます。メラトニンが、寝入る(不眠症)ことができないことのためにも、使われます; 遅延性睡眠段階症候群(DSPS); 急速眼球運動睡眠行動障害(RBD); 注意力欠陥-活動亢進障害(ADHD)を伴う不眠症; 特定の高血圧薬物による不眠症は、ベータ受容体遮断薬を呼びました; そして、自閉症、脳性麻痺と知的な障害を含む発達上の障害の子供たちの睡眠問題。ベンゾジアゼピン薬の用法をやめた後に、そして、禁煙する副作用を減らすために、それが睡眠援助としても使われます。一部の人々は、アルツハイマー病または記憶喪失(痴呆)のためにメラトニンを使います。障害、慢性閉塞性肺疾患(COPD)と呼ばれている肺疾患、ベータ受容体遮断薬薬に起因する不眠症、子宮内膜症のために、一部の人々はメラトニンを使います。そして、耳、落ち込みまたは季節性感情障害(SAD)、軽い精神的欠陥、アルコールを含まない肝疾患、慢性疲労症候群(CFS)、線維筋痛、絶え間ない足症候群を取り囲みます。そして、炎症性病気がサルコイドーシス、精神分裂症、片頭痛と他頭痛、年齢に関連する視力損失、良性前立腺過形成(BPH)、過敏性大腸症候群(IBS)、骨損失(骨粗鬆症)、遅行性顔面麻痺(TD)と呼ばれている運動障害と呼ばれています。酸性の逆流病、ヘリコバクターピロリ(H. pylori)、運動パフォーマンス、不妊性、癲癇、手術後の回復、麻酔に起因する動揺、ストレス、不随意運動障害(遅行性顔面麻痺)、定めることから体を起こす(姿勢の心搏急速症候群)ことに、貴社が移る心拍数の変化、精神錯乱、排尿をコントロールすることができないこと、あごの痛み、炎症性腸疾患(潰瘍性大腸炎)のための更年期(メタボリックシンドローム)のために、老化のために、そして、産児制限のために、一部の人々は、メラトニンを使います。 ... 詳細
3mg